Noninvasive PK11195‐PET Image Analysis Techniques Can Detect Abnormal Cerebral Microglial Activation in Parkinson's Disease

BACKGROUND AND PURPOSE: Neuroinflammation has been implicated in the pathophysiology of Parkinson's disease (PD), which might be influenced by successful neuroprotective drugs. The uptake of [(11)C](R)‐PK11195 (PK) is often considered to be a proxy for neuroinflammation, and can be quantified u...

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Vydáno v:J Neuroimaging
Hlavní autoři: Kang, Yeona, Mozley, P. David, Verma, Ajay, Schlyer, David, Henchcliffe, Claire, Gauthier, Susan A., Chiao, Ping C., He, Bin, Nikolopoulou, Anastasia, Logan, Jean, Sullivan, Jenna M., Pryor, Kane O., Hesterman, Jacob, Kothari, Paresh J., Vallabhajosula, Shankar
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2018
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6174975/
https://ncbi.nlm.nih.gov/pubmed/29727504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jon.12519
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