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Influence of mutation bias and hydrophobicity on the substitution rates and sequence entropies of protein evolution

The number of amino acids that occupy a given protein site during evolution reflects the selective constraints operating on the site. This evolutionary variability is strongly influenced by the structural properties of the site in the native structure, and it is quantified either through sequence en...

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Detalhes bibliográficos
Publicado no:PeerJ
Main Authors: Jiménez-Santos, María José, Arenas, Miguel, Bastolla, Ugo
Formato: Artigo
Idioma:Inglês
Publicado em: PeerJ Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6174885/
https://ncbi.nlm.nih.gov/pubmed/30310736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.5549
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