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Sequence entropy of folding and the absolute rate of amino acid substitutions
Adequate representations of protein evolution should consider how the acceptance of mutations depends on the sequence context in which they arise. However, epistatic interactions among sites in a protein result in time and spatial substitution rate heterogeneity beyond the capabilities of current mo...
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| Publicado no: | Nat Ecol Evol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5701738/ https://ncbi.nlm.nih.gov/pubmed/29062121 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41559-017-0338-9 |
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