Does clinical outcome of birch pollen immunotherapy relate to induction of blocking antibodies preventing IgE from allergen binding? A pilot study monitoring responses during first year of AIT

BACKGROUND: The clinical benefit of allergen-specific immunotherapy (AIT) involves induction of blocking antibodies. It is not clear if these antibodies function via steric hindrance alone or a combination of levels, avidities, and epitope specificities, and clinical outcome cannot be predicted. We...

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Veröffentlicht in:Clin Transl Allergy
Hauptverfasser: Huber, Sara, Lang, Roland, Steiner, Markus, Aglas, Lorenz, Ferreira, Fatima, Wallner, Michael, Hawranek, Thomas, Gadermaier, Gabriele
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2018
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Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6174570/
https://ncbi.nlm.nih.gov/pubmed/30338052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13601-018-0226-7
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