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Determination of allergen specificity by heavy chains in grass pollen allergen–specific IgE antibodies

BACKGROUND: Affinity and clonality of allergen-specific IgE antibodies are important determinants for the magnitude of IgE-mediated allergic inflammation. OBJECTIVE: We sought to analyze the contribution of heavy and light chains of human allergen-specific IgE antibodies for allergen specificity and...

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Detalhes bibliográficos
Main Authors: Gadermaier, Elisabeth, Flicker, Sabine, Lupinek, Christian, Steinberger, Peter, Valenta, Rudolf
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3778255/
https://ncbi.nlm.nih.gov/pubmed/23206656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2012.10.010
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