POxylated Dendrimer‐Based Nano‐in‐Micro Dry Powder Formulations for Inhalation Chemotherapy

POxylated polyurea dendrimer (PURE(G4)OOx(48))‐based nanoparticles were loaded with paclitaxel (PTX) and doxorubicin (DOX) and micronized with chitosan (CHT) by using supercritical CO(2)‐assisted spray drying (SASD). Respirable, biocompatible, and biodegradable dry powder formulations (DPFs) were pr...

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Bibliographic Details
Published in:ChemistryOpen
Main Authors: Restani, Rita B., Pires, Rita F., Tolmatcheva, Anna, Cabral, Rita, Baptista, Pedro V., Fernandes, Alexandra R., Casimiro, Teresa, Bonifácio, Vasco D. B., Aguiar‐Ricardo, Ana
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6174550/
https://ncbi.nlm.nih.gov/pubmed/30338202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/open.201800093
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