POxylated Dendrimer‐Based Nano‐in‐Micro Dry Powder Formulations for Inhalation Chemotherapy

POxylated polyurea dendrimer (PURE(G4)OOx(48))‐based nanoparticles were loaded with paclitaxel (PTX) and doxorubicin (DOX) and micronized with chitosan (CHT) by using supercritical CO(2)‐assisted spray drying (SASD). Respirable, biocompatible, and biodegradable dry powder formulations (DPFs) were pr...

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Publicado no:ChemistryOpen
Main Authors: Restani, Rita B., Pires, Rita F., Tolmatcheva, Anna, Cabral, Rita, Baptista, Pedro V., Fernandes, Alexandra R., Casimiro, Teresa, Bonifácio, Vasco D. B., Aguiar‐Ricardo, Ana
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6174550/
https://ncbi.nlm.nih.gov/pubmed/30338202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/open.201800093
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