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Disease Modifiers of Inherited SCN5A Channelopathy

To date, a large number of mutations in SCN5A, the gene encoding the pore-forming α-subunit of the primary cardiac Na(+) channel (Na(V)1.5), have been found in patients presenting with a wide range of ECG abnormalities and cardiac syndromes. Although these mutations all affect the same Na(V)1.5 chan...

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書目詳細資料
發表在:Front Cardiovasc Med
Main Authors: Verkerk, Arie O., Amin, Ahmad S., Remme, Carol Ann
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6174200/
https://ncbi.nlm.nih.gov/pubmed/30327767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcvm.2018.00137
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