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Quantitative evaluation of tau PET tracers (18)F-THK5351 and (18)F-AV-1451 in Alzheimer’s disease with standardized uptake value peak-alignment (SUVP) normalization
PURPOSE: Off-target binding in the reference region is a challenge for recent tau tracers (18)F-AV-1451 and (18)F-THK5351. The conventional standardized uptake value ratio (SUVR) method relies on the average uptake from an unaffected tissue sample, and therefore is susceptible to biases from off-tar...
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Udgivet i: | Eur J Nucl Med Mol Imaging |
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Main Authors: | , , , , , |
Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
2018
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6174003/ https://ncbi.nlm.nih.gov/pubmed/29704038 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00259-018-4040-1 |
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