ZNF341 controls STAT3 expression and thereby immunocompetence

Signal-transducer-and-activator-of-transcription-3 (STAT3) is a central regulator of immune homeostasis. STAT3 levels are strictly controlled and STAT3 impairment contributes to several diseases including the monogenic autosomal-dominant hyper-IgE syndrome (AD-HIES). We investigated patients of four...

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Publicat a:Sci Immunol
Autors principals: Frey-Jakobs, Stefanie, Hartberger, Julia M., Fliegauf, Manfred, Bossen, Claudia, Wehmeyer, Magdalena L., Neubauer, Johanna C., Bulashevska, Alla, Proietti, Michele, Fröbel, Philipp, Nöltner, Christina, Yang, Linlin, Rojas-Restrepo, Jessica, Langer, Niko, Winzer, Sandra, Engelhardt, Karin R., Glocker, Cristina, Pfeifer, Dietmar, Klein, Adi, Schäffer, Alejandro A., Lagovsky, Irina, Lachover-Roth, Idit, Béziat, Vivien, Puel, Anne, Casanova, Jean-Laurent, Fleckenstein, Bernhard, Weidinger, Stephan, Kilic, Sara S., Garty, Ben-Zion, Etzioni, Amos, Grimbacher, Bodo
Format: Artigo
Idioma:Inglês
Publicat: 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6173313/
https://ncbi.nlm.nih.gov/pubmed/29907690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciimmunol.aat4941
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