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ESS: A Tool for Genome-Scale Quantification of Essentiality Score for Reaction/Genes in Constraint-Based Modeling

Genome-scale metabolic models (GEMs) are comprehensive descriptions of cell metabolism and have been extensively used to understand biological responses in health and disease. One such application is in determining metabolic adaptation to the absence of a gene or reaction, i.e., essentiality analysi...

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Bibliografske podrobnosti
izdano v:Front Physiol
Main Authors: Zhang, Cheng, Bidkhori, Gholamreza, Benfeitas, Rui, Lee, Sunjae, Arif, Muhammad, Uhlén, Mathias, Mardinoglu, Adil
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6173058/
https://ncbi.nlm.nih.gov/pubmed/30323767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2018.01355
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