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ESS: A Tool for Genome-Scale Quantification of Essentiality Score for Reaction/Genes in Constraint-Based Modeling

Genome-scale metabolic models (GEMs) are comprehensive descriptions of cell metabolism and have been extensively used to understand biological responses in health and disease. One such application is in determining metabolic adaptation to the absence of a gene or reaction, i.e., essentiality analysi...

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Detalhes bibliográficos
Publicado no:Front Physiol
Main Authors: Zhang, Cheng, Bidkhori, Gholamreza, Benfeitas, Rui, Lee, Sunjae, Arif, Muhammad, Uhlén, Mathias, Mardinoglu, Adil
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6173058/
https://ncbi.nlm.nih.gov/pubmed/30323767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2018.01355
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