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Activated natural killer T cells in mice induce acute kidney injury with hematuria through possibly common mechanisms shared by human CD56(+) T cells

Although activation of mouse natural killer T (NKT) cells by α-galactosylceramide (α-GalCer) causes failure of multiple organs, including the kidneys, the precise mechanisms underlying kidney injury remain unclear. Here, we showed that α-GalCer-activated mouse NKT cells injured both kidney vascular...

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Detalhes bibliográficos
Publicado no:Am J Physiol Renal Physiol
Main Authors: Uchida, Takahiro, Nakashima, Hiroyuki, Ito, Seigo, Ishikiriyama, Takuya, Nakashima, Masahiro, Seki, Shuhji, Kumagai, Hiroo, Oshima, Naoki
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6172573/
https://ncbi.nlm.nih.gov/pubmed/29993279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00160.2018
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