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Repeated administration of alpha-galactosylceramide ameliorates experimental lupus nephritis in mice

Lupus nephritis is a crucial complication of systemic lupus erythematosus. In this study, we investigated the roles of mouse natural killer T (NKT) cells in lupus nephritis. From 24 weeks of age, NZB/NZW F1 mice were injected with alpha-galactosylceramide (α-GalCer) or vehicle once a week for four w...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Uchida, Takahiro, Nakashima, Hiroyuki, Yamagata, Akira, Ito, Seigo, Ishikiriyama, Takuya, Nakashima, Masahiro, Seki, Shuhji, Kumagai, Hiroo, Oshima, Naoki
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5974230/
https://ncbi.nlm.nih.gov/pubmed/29844470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-26470-w
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