Tanshinone IIA promotes the apoptosis of fibroblast-like synoviocytes in rheumatoid arthritis by up-regulating lncRNA GAS5

Rheumatoid arthritis (RA) is a common chronic autoimmune joint disease characteristic of elevated proliferation and infiltration of fibroblast-like synoviocytes (FLS). Here, we aimed to explore the mechanisms of the Tanshinone IIA (Tan IIA)-induced apoptosis of FLS from patients with RA (termed RAFL...

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Publicat a:Biosci Rep
Autors principals: Li, Guoqing, Liu, Ying, Meng, Fanru, Xia, Zhongbin, Wu, Xia, Fang, Yuxuan, Zhang, Chunwang, Liu, Dan
Format: Artigo
Idioma:Inglês
Publicat: Portland Press Ltd. 2018
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6172423/
https://ncbi.nlm.nih.gov/pubmed/30232236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20180626
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