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Adoptive transfer of xenoantigen-stimulated T cell receptor Vβ-restricted human regulatory T cells prevents porcine islet xenograft rejection in humanized mice

Polyclonal expansion of human regulatory T cells (Tregs) prevents xenogeneic rejection by suppressing effector T cell responses in vitro and in vivo. However, a major limitation to using polyclonally expanded Tregs is that they may cause pan-immunosuppressive effects. The present study was conducted...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Mol Med Rep
Main Authors: Jin, Xi, Hu, Min, Gong, Lina, Li, Huifang, Wang, Yan, Ji, Ming, Li, Hong
Format: Artigo
Jezik:Inglês
Izdano: D.A. Spandidos 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6172378/
https://ncbi.nlm.nih.gov/pubmed/30221725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2018.9471
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