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Regulation of the NLRP3 inflammasome and macrophage pyroptosis by the p38 MAPK signaling pathway in a mouse model of acute lung injury

Acute lung injury and acute respiratory distress syndrome (ALI/ARDS) is characterized by uncontrolled progressive lung inflammation. Macrophages serve a key role in the pathogenesis of ALI/ARDS. Macrophage pyroptosis is a process of cell death releasing the proinflammatory cytokines interleukin (IL)...

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Pubblicato in:Mol Med Rep
Autori principali: Li, Dandan, Ren, Weiying, Jiang, Zhilong, Zhu, Lei
Natura: Artigo
Lingua:Inglês
Pubblicazione: D.A. Spandidos 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6172370/
https://ncbi.nlm.nih.gov/pubmed/30152849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2018.9427
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