Lack of FcRn Impairs Natural Killer Cell Development and Functions in the Tumor Microenvironment

The neonatal Fc receptor (FcRn) is responsible for the recycling and transcytosis of IgG and albumin. FcRn level was found altered in cancer tissues and implicated in tumor immunosurveillance and neoplastic cell growth. However, the consequences of FcRn down-regulation in the anti-tumor immune respo...

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Detalles Bibliográficos
Publicado en:Front Immunol
Main Authors: Castaneda, Diana Cadena, Dhommée, Christine, Baranek, Thomas, Dalloneau, Emilie, Lajoie, Laurie, Valayer, Alexandre, Arnoult, Christophe, Demattéi, Marie-Véronique, Fouquenet, Delphine, Parent, Christelle, Heuzé-Vourc'h, Nathalie, Gouilleux-Gruart, Valérie
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2018
Assuntos:
Immunology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6172308/
https://ncbi.nlm.nih.gov/pubmed/30323819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02259
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