Ablation of a Single N-Glycosylation Site in Human FSTL 1 Induces Cardiomyocyte Proliferation and Cardiac Regeneration

Adult mammalian hearts have a very limited regeneration capacity, due largely to a lack of cardiomyocyte (CM) proliferation. It was recently reported that epicardial, but not myocardial, follistatin-like 1 (Fstl1) activates CM proliferation and cardiac regeneration after myocardial infarction (MI)....

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Publicado en:Mol Ther Nucleic Acids
Autores principales: Magadum, Ajit, Singh, Neha, Kurian, Ann Anu, Sharkar, Mohammad Tofael Kabir, Chepurko, Elena, Zangi, Lior
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Gene & Cell Therapy 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6171324/
https://ncbi.nlm.nih.gov/pubmed/30290305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2018.08.021
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