Blocking Macrophage Migration Inhibitory Factor Protects Against Cisplatin-Induced Acute Kidney Injury in Mice

Macrophage migration inhibitory factor (MIF) is elevated in patients with acute kidney injury (AKI) and is suggested as a potential predictor for renal replacement therapy in AKI. In this study, we found that MIF also plays a pathogenic role and is a therapeutic target for AKI. In a cisplatin-induce...

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Vydáno v:Mol Ther
Hlavní autoři: Li, Jinhong, Tang, Ying, Tang, Patrick M.K., Lv, Jun, Huang, Xiao-ru, Carlsson-Skwirut, Christine, Da Costa, Lydie, Aspesi, Anna, Fröhlich, Suada, Szczęśniak, Pawel, Lacher, Philipp, Klug, Jörg, Meinhardt, Andreas, Fingerle-Rowson, Günter, Gong, Rujun, Zheng, Zhihua, Xu, Anping, Lan, Hui-yao
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Gene & Cell Therapy 2018
Témata:
Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6171075/
https://ncbi.nlm.nih.gov/pubmed/30077612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2018.07.014
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