Pharmacokinetics and safety/efficacy of levodopa pro-drug ONO-2160/carbidopa for Parkinson's disease

We conducted a phase I study investigating the efficacy, safety, and tolerability of ONO-2160, a newly developed levodopa pro-drug, and carbidopa compared with levodopa and carbidopa to stabilize levodopa plasma concentration fluctuations in Japanese patients with Parkinson's disease. In an ope...

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Detalhes bibliográficos
Publicado no:eNeurologicalSci
Main Authors: Nomoto, Masahiro, Nagai, Masahiro, Nishikawa, Noriko, Ando, Rina, Kagamiishi, Yoshifumi, Yano, Koji, Saito, Shigeto, Takeda, Atsushi
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6171046/
https://ncbi.nlm.nih.gov/pubmed/30294682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ensci.2018.09.003
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