ZO-1 protein is required for hydrogen peroxide to increase MDCK cell paracellular permeability in an ERK 1/2-dependent manner

Hydrogen peroxide (H(2)O(2)) increases paracellular permeability of Madin-Darby canine kidney (MDCK) cells, but the mechanism mediating this effect remains unclear. Treatment of MDCK cells with H(2)O(2) activated ERK 1/2. Inhibition of ERK 1/2 activation blocked the ability of H(2)O(2) to increase p...

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Publicat a:Am J Physiol Cell Physiol
Autors principals: Bilal, Sahar, Jaggi, Shirin, Janosevic, Danielle, Shah, Nikita, Teymour, Shereen, Voronina, Angelina, Watari, Jessica, Axis, Josephine, Amsler, Kurt
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2018
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6171043/
https://ncbi.nlm.nih.gov/pubmed/29874107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00185.2017
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