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A1899, PK‐THPP, ML365, and Doxapram inhibit endogenous TASK channels and excite calcium signaling in carotid body type‐1 cells
Sensing of hypoxia and acidosis in arterial chemoreceptors is thought to be mediated through the inhibition of TASK and possibly other (e.g., BK(C) (a)) potassium channels which leads to membrane depolarization, voltage‐gated Ca‐entry, and neurosecretion. Here, we investigate the effects of pharmaco...
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| Publicado no: | Physiol Rep |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6170881/ https://ncbi.nlm.nih.gov/pubmed/30284397 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.13876 |
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