Structures of Hepatitis B Virus core- and e-antigen Immune-complexes Suggest Multi-Point Inhibition

Hepatitis B virus (HBV) is the leading cause of liver disease worldwide. While an adequate vaccine is available, current treatment options are limited, not highly effective, and associated with adverse effects, encouraging the development of alternative therapeutics. The HBV core gene encodes two di...

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Veröffentlicht in:Structure
Hauptverfasser: Eren, Elif, Watts, Norman R., Dearborn, Altaira D., Palmer, Ira W., Kaufman, Joshua D., Steven, Alasdair C., Wingfield, Paul T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6170708/
https://ncbi.nlm.nih.gov/pubmed/30100358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2018.06.012
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