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An Atomistic Model of a Precursor State of Light-Induced Channel Opening of Channelrhodopsin

Channelrhodopsins (ChRs) are microbial light-gated ion channels with a retinal chromophore and are widely utilized in optogenetics to precisely control neuronal activity with light. Despite increasing understanding of their structures and photoactivation kinetics, the atomistic mechanism of light ga...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Cheng, Cheng, Kamiya, Motoshi, Takemoto, Mizuki, Ishitani, Ryuichiro, Nureki, Osamu, Yoshida, Norio, Hayashi, Shigehiko
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6170652/
https://ncbi.nlm.nih.gov/pubmed/30236783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2018.08.024
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