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Atomistic design of microbial opsin-based blue-shifted optogenetics tools

Microbial opsins with a bound chromophore function as photosensitive ion transporters and have been employed in optogenetics for the optical control of neuronal activity. Molecular engineering has been utilized to create colour variants for the functional augmentation of optogenetics tools, but was...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Kato, Hideaki E., Kamiya, Motoshi, Sugo, Seiya, Ito, Jumpei, Taniguchi, Reiya, Orito, Ayaka, Hirata, Kunio, Inutsuka, Ayumu, Yamanaka, Akihiro, Maturana, Andrés D., Ishitani, Ryuichiro, Sudo, Yuki, Hayashi, Shigehiko, Nureki, Osamu
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Pub. Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4479019/
https://ncbi.nlm.nih.gov/pubmed/25975962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8177
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