STAT3 associates with vacuolar H(+)-ATPase and regulates cytosolic and lysosomal pH

Dysregulated intracellular pH is emerging as a hallmark of cancer. In spite of their acidic environment and increased acid production, cancer cells maintain alkaline intracellular pH that promotes cancer progression by inhibiting apoptosis and increasing glycolysis, cell growth, migration, and invas...

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Bibliografiske detaljer
Udgivet i:Cell Res
Main Authors: Liu, Bin, Palmfeldt, Johan, Lin, Lin, Colaço, Alexandria, Clemmensen, Knut K. B., Huang, Jinrong, Xu, Fengping, Liu, Xin, Maeda, Kenji, Luo, Yonglun, Jäättelä, Marja
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6170402/
https://ncbi.nlm.nih.gov/pubmed/30127373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41422-018-0080-0
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