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STAT3 associates with vacuolar H(+)-ATPase and regulates cytosolic and lysosomal pH
Dysregulated intracellular pH is emerging as a hallmark of cancer. In spite of their acidic environment and increased acid production, cancer cells maintain alkaline intracellular pH that promotes cancer progression by inhibiting apoptosis and increasing glycolysis, cell growth, migration, and invas...
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| Опубликовано в: : | Cell Res |
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| Главные авторы: | , , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group UK
2018
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6170402/ https://ncbi.nlm.nih.gov/pubmed/30127373 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41422-018-0080-0 |
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