STAT3 associates with vacuolar H(+)-ATPase and regulates cytosolic and lysosomal pH

Dysregulated intracellular pH is emerging as a hallmark of cancer. In spite of their acidic environment and increased acid production, cancer cells maintain alkaline intracellular pH that promotes cancer progression by inhibiting apoptosis and increasing glycolysis, cell growth, migration, and invas...

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Publicat a:Cell Res
Autors principals: Liu, Bin, Palmfeldt, Johan, Lin, Lin, Colaço, Alexandria, Clemmensen, Knut K. B., Huang, Jinrong, Xu, Fengping, Liu, Xin, Maeda, Kenji, Luo, Yonglun, Jäättelä, Marja
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6170402/
https://ncbi.nlm.nih.gov/pubmed/30127373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41422-018-0080-0
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