Exosomal 15-LO2 mediates hypoxia-induced pulmonary artery hypertension in vivo and in vitro

Our previous studies have shown that 15-LO2/15-HETE induced by hypoxia played an important role in pulmonary arterial hypertension (PH). However, the transportations of 15-LO2/15-HETE among the cells remain elusive. In this study, we investigated the specific involvement of 15-LO2-containing exosome...

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Publicat a:Cell Death Dis
Autors principals: Zhang, Min, Xin, Wei, Ma, Cui, Zhang, Hongyue, Mao, Min, Liu, Ying, Zheng, Xiaodong, Zhang, Lixin, Yu, Xiufeng, Li, Huajian, Zhu, Daling
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6170379/
https://ncbi.nlm.nih.gov/pubmed/30282973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-1073-0
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