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Paradoxically Elevated Efavirenz Concentrations in HIV/TB Co-infected Patients with CYP2B6 516TT Genotype on Rifampin-containing Antituberculous Therapy
Some individuals have higher efavirenz plasma concentrations during rifampin-containing tuberculosis (TB) therapy, contrary to the expected induction effect of rifampin. Among HIV-infected patients without (N=38) and with TB on rifampin-containing therapy (N=18), we tested the hypothesis that drug-g...
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| Veröffentlicht in: | AIDS |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6170200/ https://ncbi.nlm.nih.gov/pubmed/21150552 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0b013e3283427e05 |
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