Paradoxically Elevated Efavirenz Concentrations in HIV/TB Co-infected Patients with CYP2B6 516TT Genotype on Rifampin-containing Antituberculous Therapy

Some individuals have higher efavirenz plasma concentrations during rifampin-containing tuberculosis (TB) therapy, contrary to the expected induction effect of rifampin. Among HIV-infected patients without (N=38) and with TB on rifampin-containing therapy (N=18), we tested the hypothesis that drug-g...

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Publicado en:AIDS
Autores principales: Kwara, Awewura, Lartey, Margaret, Sagoe, Kwamena W., Court, Michael H.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6170200/
https://ncbi.nlm.nih.gov/pubmed/21150552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0b013e3283427e05
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