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Fusion surface structure, function, and dynamics of gamete fusogen HAP2
HAP2 is a class II gamete fusogen in many eukaryotic kingdoms. A crystal structure of Chlamydomonas HAP2 shows a trimeric fusion state. Domains D1, D2.1 and D2.2 line the 3-fold axis; D3 and a stem pack against the outer surface. Surprisingly, hydrogen-deuterium exchange shows that surfaces of D1, D...
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| Publicado no: | eLife |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
eLife Sciences Publications, Ltd
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6170185/ https://ncbi.nlm.nih.gov/pubmed/30281023 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.39772 |
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