Načítá se...
Structural features and domain movements controlling substrate binding and cofactor specificity in class II HMG-CoA reductase
The key mevalonate pathway enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase (HMGR) uses the cofactor NAD(P)H to reduce HMG-CoA to mevalonate in the production of countless metabolites and natural products. Although HMGR inhibition by statin drugs is well understood, several mechanist...
Uloženo v:
| Vydáno v: | Biochemistry |
|---|---|
| Hlavní autoři: | , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2017
|
| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6170158/ https://ncbi.nlm.nih.gov/pubmed/29224355 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.7b00999 |
| Tagy: |
Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!
|