A Batf3/Nlrp3/IL-18 Axis Promotes Natural Killer Cell IL-10 Production during Listeria monocytogenes Infection

The bacterial pathogen Listeria monocytogenes (Lm) capitalizes on natural killer (NK) cell production of regulatory interleukin (IL)-10 to establish severe systemic infections. Here, we identify regulators of this IL-10 secretion. We show that IL-18 signals to NK cells license their ability to produ...

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發表在:Cell Rep
Main Authors: Clark, Sarah E., Schmidt, Rebecca L., McDermott, Daniel S., Lenz, Laurel L.
格式: Artigo
語言:Inglês
出版: 2018
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6170157/
https://ncbi.nlm.nih.gov/pubmed/29847790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.04.106
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