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Gating interaction maps reveal a noncanonical electromechanical coupling mode in the Shaker K(+) channel
Membrane potential regulates the activity of voltage-dependent ion channels via specialized voltage-sensing modules but the mechanisms involved in coupling voltage-sensor movement to pore opening remain unclear due to lack of resting state structures and robust methods to identify allosteric pathway...
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| Publicado no: | Nat Struct Mol Biol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6170002/ https://ncbi.nlm.nih.gov/pubmed/29581567 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41594-018-0047-3 |
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