Chaperone-Mediated Autophagy Promotes Beclin1 Degradation in Persistently Infected Hepatitis C Virus Cell Culture

Liver cirrhosis is an independent risk factor for hepatocellular carcinoma (HCC). The mechanisms that contribute to HCC development in the cirrhotic microenvironment are unknown. We found that HCC grown in the highly stressed cirrhotic microenvironment undergoes autophagy switching from a protective...

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Bibliographic Details
Published in:Am J Pathol
Main Authors: Aydin, Yucel, Stephens, Christopher M., Chava, Srinivas, Heidari, Zahra, Panigrahi, Rajesh, Williams, Donkita D., Wiltz, Kylar, Bell, Antoinette, Wilson, Wallace, Reiss, Krzysztof, Dash, Srikanta
Format: Artigo
Language:Inglês
Published: American Society for Investigative Pathology 2018
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6168955/
https://ncbi.nlm.nih.gov/pubmed/30075149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2018.06.022
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