Chaperone-Mediated Autophagy Targets IFNAR1 for Lysosomal Degradation in Free Fatty Acid Treated HCV Cell Culture

BACKGROUND: Hepatic steatosis is a risk factor for both liver disease progression and an impaired response to interferon alpha (IFN-α)-based combination therapy in chronic hepatitis C virus (HCV) infection. Previously, we reported that free fatty acid (FFA)-treated HCV cell culture induces hepatocel...

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Bibliografiska uppgifter
I publikationen:PLoS One
Huvudupphovsmän: Kurt, Ramazan, Chandra, Partha K., Aboulnasr, Fatma, Panigrahi, Rajesh, Ferraris, Pauline, Aydin, Yucel, Reiss, Krzysztof, Wu, Tong, Balart, Luis A., Dash, Srikanta
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2015
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4427131/
https://ncbi.nlm.nih.gov/pubmed/25961570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0125962
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