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Cell cycle-resolved chromatin proteomics reveals the extent of mitotic preservation of the genomic regulatory landscape

Regulation of transcription, replication, and cell division relies on differential protein binding to DNA and chromatin, yet it is unclear which regulatory components remain bound to compacted mitotic chromosomes. By utilizing the buoyant density of DNA–protein complexes after cross-linking, we here...

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Библиографические подробности
Опубликовано в: :Nat Commun
Главные авторы: Ginno, Paul Adrian, Burger, Lukas, Seebacher, Jan, Iesmantavicius, Vytautas, Schübeler, Dirk
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6168604/
https://ncbi.nlm.nih.gov/pubmed/30279501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06007-5
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