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Cell cycle-resolved chromatin proteomics reveals the extent of mitotic preservation of the genomic regulatory landscape

Regulation of transcription, replication, and cell division relies on differential protein binding to DNA and chromatin, yet it is unclear which regulatory components remain bound to compacted mitotic chromosomes. By utilizing the buoyant density of DNA–protein complexes after cross-linking, we here...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Ginno, Paul Adrian, Burger, Lukas, Seebacher, Jan, Iesmantavicius, Vytautas, Schübeler, Dirk
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6168604/
https://ncbi.nlm.nih.gov/pubmed/30279501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06007-5
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