Urinary Exosomal and cell-free DNA Detects Somatic Mutation and Copy Number Alteration in Urothelial Carcinoma of Bladder

Urothelial bladder carcinoma (UBC) is characterized by a large number of genetic alterations. DNA from urine is a promising source for liquid biopsy in urological malignancies. We aimed to assess the availability of cell-free DNA (cfDNA) and exosomal DNA (exoDNA) in urine as a source for liquid biop...

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Vydáno v:Sci Rep
Hlavní autoři: Lee, Dong Hyeon, Yoon, Hana, Park, Sanghui, Kim, Jeong Seon, Ahn, Young-Ho, Kwon, Kihwan, Lee, Donghwan, Kim, Kwang Hyun
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6168539/
https://ncbi.nlm.nih.gov/pubmed/30279572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-32900-6
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