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Hypoglossal motor neuron death via intralingual CTB-saporin (CTB-SAP) injections mimic aspects of amyotrophic lateral sclerosis (ALS) related to dysphagia

Amyotrophic lateral sclerosis (ALS) is a devastating disease leading to degeneration of motor neurons and skeletal muscles, including those required for swallowing. Tongue weakness is one of the earliest signs of bulbar dysfunction in ALS, which is attributed to degeneration of motor neurons in the...

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Detalhes bibliográficos
Publicado no:Neuroscience
Main Authors: Lind, Lori A., Murphy, Erika R., Lever, Teresa E., Nichols, Nicole L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6168367/
https://ncbi.nlm.nih.gov/pubmed/30179644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2018.08.026
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