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Cdt1 stabilizes kinetochore–microtubule attachments via an Aurora B kinase–dependent mechanism
Robust kinetochore–microtubule (kMT) attachment is critical for accurate chromosome segregation. G2/M-specific depletion of human Cdt1 that localizes to kinetochores in an Ndc80 complex–dependent manner leads to abnormal kMT attachments and mitotic arrest. This indicates an independent mitotic role...
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| Publicado no: | J Cell Biol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Rockefeller University Press
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6168275/ https://ncbi.nlm.nih.gov/pubmed/30154187 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201705127 |
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