Starvation induces rapid degradation of selective autophagy receptors by endosomal microautophagy

It is not clear to what extent starvation-induced autophagy affects the proteome on a global scale and whether it is selective. In this study, we report based on quantitative proteomics that cells during the first 4 h of acute starvation elicit lysosomal degradation of up to 2–3% of the proteome. Th...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Mejlvang, Jakob, Olsvik, Hallvard, Svenning, Steingrim, Bruun, Jack-Ansgar, Abudu, Yakubu Princely, Larsen, Kenneth Bowitz, Brech, Andreas, Hansen, Tom E., Brenne, Hanne, Hansen, Terkel, Stenmark, Harald, Johansen, Terje
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2018
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6168274/
https://ncbi.nlm.nih.gov/pubmed/30018090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201711002
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