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Myoepithelial cells are a dynamic barrier to epithelial dissemination

The mammary epithelium is composed of an inner luminal and surrounding myoepithelial cell layer. The presence of cancer cells beyond the myoepithelium defines invasive breast cancer, yet the role of the myoepithelium during invasion remains unclear. We developed a 3D organotypic culture assay to mod...

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Pubblicato in:J Cell Biol
Autori principali: Sirka, Orit Katarina, Shamir, Eliah R., Ewald, Andrew J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Rockefeller University Press 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6168248/
https://ncbi.nlm.nih.gov/pubmed/30061105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201802144
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