Aging alters the epigenetic asymmetry of HSC division

Hematopoietic stem cells (HSCs) balance self-renewal and differentiation to maintain homeostasis. With aging, the frequency of polar HSCs decreases. Cell polarity in HSCs is controlled by the activity of the small RhoGTPase cell division control protein 42 (Cdc42). Here we demonstrate—using a compre...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:PLoS Biol
Main Authors: Florian, M. Carolina, Klose, Markus, Sacma, Mehmet, Jablanovic, Jelena, Knudson, Luke, Nattamai, Kalpana J., Marka, Gina, Vollmer, Angelika, Soller, Karin, Sakk, Vadim, Cabezas-Wallscheid, Nina, Zheng, Yi, Mulaw, Medhanie A., Glauche, Ingmar, Geiger, Hartmut
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6168157/
https://ncbi.nlm.nih.gov/pubmed/30235201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.2003389
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados