Duplex Proximity Sequencing (Pro-Seq): A method to improve DNA sequencing accuracy without the cost of molecular barcoding redundancy

A challenge in the clinical adoption of cell-free DNA (cfDNA) liquid biopsies for cancer care is their high cost compared to potential reimbursement. The most common approach used in liquid biopsies to achieve high specificity detection of circulating tumor DNA (ctDNA) among a large background of no...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Pel, Joel, Choi, Wendy W. Y., Leung, Amy, Shibahara, Gosuke, Gelinas, Laura, Despotovic, Milenko, Ung, W. Lloyd, Marziali, Andre
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6168144/
https://ncbi.nlm.nih.gov/pubmed/30278055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0204265
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