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Duplex Proximity Sequencing (Pro-Seq): A method to improve DNA sequencing accuracy without the cost of molecular barcoding redundancy

A challenge in the clinical adoption of cell-free DNA (cfDNA) liquid biopsies for cancer care is their high cost compared to potential reimbursement. The most common approach used in liquid biopsies to achieve high specificity detection of circulating tumor DNA (ctDNA) among a large background of no...

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Detaylı Bibliyografya
Yayımlandı:PLoS One
Asıl Yazarlar: Pel, Joel, Choi, Wendy W. Y., Leung, Amy, Shibahara, Gosuke, Gelinas, Laura, Despotovic, Milenko, Ung, W. Lloyd, Marziali, Andre
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6168144/
https://ncbi.nlm.nih.gov/pubmed/30278055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0204265
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