Impact of ZBTB7A hypomethylation and expression patterns on treatment response to hydroxyurea

BACKGROUND: We aimed to clarify the emerging epigenetic landscape in a group of genes classified as “modifier genes” of the β-type globin genes (HBB cluster), known to operate in trans to accomplish the two natural developmental switches in globin expression, from embryonic to fetal during the first...

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Detalhes bibliográficos
Publicado no:Hum Genomics
Main Authors: Chondrou, Vasiliki, Stavrou, Eleana F., Markopoulos, Georgios, Kouraklis-Symeonidis, Alexandra, Fotopoulos, Vasilios, Symeonidis, Argiris, Vlachaki, Efthymia, Chalkia, Panagiota, Patrinos, George P., Papachatzopoulou, Adamantia, Sgourou, Argyro
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Primary Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6167880/
https://ncbi.nlm.nih.gov/pubmed/30285874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40246-018-0177-z
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