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N-cadherin in cancer metastasis, its emerging role in haematological malignancies and potential as a therapeutic target in cancer

In many types of solid tumours, the aberrant expression of the cell adhesion molecule N-cadherin is a hallmark of epithelial-to-mesenchymal transition, resulting in the acquisition of an aggressive tumour phenotype. This transition endows tumour cells with the capacity to escape from the confines of...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Mrozik, Krzysztof Marek, Blaschuk, Orest William, Cheong, Chee Man, Zannettino, Andrew Christopher William, Vandyke, Kate
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6167798/
https://ncbi.nlm.nih.gov/pubmed/30285678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-018-4845-0
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