Depicting Changes in Tumor Biology in Response to Cetuximab Monotherapy or Combination Therapy by Apoptosis and Proliferation Imaging Using (18)F-ICMT-11 and (18)F-FLT PET

Imaging biomarkers must demonstrate their value in monitoring treatment. Two PET tracers, the caspase-3/7–specific isatin-5-sulfonamide (18)F-ICMT-11 ((18)F-(S)-1-((1-(2-fluoroethyl)-1H-[1,2,3]-triazol-4-yl)methyl)-5-(2(2,4-difluoro-phenoxymethyl)-pyrrolidine-1-sulfonyl)isatin) and (18)F-FLT (3′-deo...

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Detalhes bibliográficos
Publicado no:J Nucl Med
Main Authors: Heinzmann, Kathrin, Nguyen, Quang-Dé, Honess, Davina, Smith, Donna-Michelle, Stribbling, Stephen, Brickute, Diana, Barnes, Chris, Griffiths, John, Aboagye, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: Society of Nuclear Medicine 2018
Assuntos:
Oncology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6167530/
https://ncbi.nlm.nih.gov/pubmed/29794225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.118.209304
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